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Overview
•

Drafted out by American College of Cardiology (ACC) and American Heart
Association (AHA) initially in 1980 then revised again in 2002, 2007 and 2011.

•

Comprising almost 20 topics relating to cardiac issues for patients undergoing
non cardiac surgery.

•

Eg : preoperative noninvasive evaluation of LV function; preoperative resting
12-lead ECG; noninvasive stress testing before non-cardiac surgery;
reoperative coronary revascularization; betablocker therapy; statin therapy;
preoperative ICU monitoring; use of volatile anesthetic agents; prophylactic
Nitroglycerin, maintenance of normothermia; glucose control; use of
pulmonary artery catheters; intraoperative and postoperative ST-segment
monitoring; surveillance for perioperative myocardial infarction; and the
tissue of when patients with cardiac stents can safely undergo elective surgery
Purpose
•

Quick reference for decision making

•

lower the risk of surgery

•

evaluation of the patient’s current medical status

•

make recommendations concerning the evaluation,
management, and risk of cardiac problems over the entire
preoperative period

•

provide a clinical risk profile can be of use in making treatment
decisions that may influence short- and long-term cardiac
outcomes
GOALS
– IDENTIFICATION OF PATIENTS WITH UNSTABLE
CARDIOVASCULAR CONDITION
– IDENTIFICATION OF PATIENTS WITH KNOWN AND
SYMPTOMATIC Coronary Heart Disease (CHD)
– IDENTIFICATION OF PATIENTS AT RISK OF CHD
»
»
»
»
»

PVD
HTN
DM
SMOKING
HYPERCHOLESTROLEMIA
CLASSIFICATION OF RECOMMENDATIONS
CLASS 1

CLASS II A

CLASS II B

CLASS III

SHOULD

REASONABLE

MAYBE
CONSIDERED

SHOULD NOT

Benefit >>>
Risk

LEVEL A
Multiple (3-5)
population risk
LEVEL B
Limited (2-3)
population risk
LEVEL C
Very limited
(1-2)
population risk

BENEFIT >>
RISK

BENEFIT >
RISK

RISK >
BENEFIT
PREOPERATIVE CARDIAC EVALUATION
•

Evaluation
History taking

•

to identify serious cardiac conditions such as unstable coronary syndromes,
prior angina, recent or past MI, decompensated HF, significant arrhythmias,
and severe valvular disease

•

history of a pacemaker or implantable cardioverter defibrillator

•

Accurate recording of current medications used, including herbal and other
nutritional supplements, and dosages

.
•

Determine ASA status , surgery classification and functional capacity.
Status

State

Class 1

No organic, physiologic, biochemical, or psychiatric
disturbance.

Class 2

Mild to moderate systemic disturbance that may or may
not be related to the reason for surgery
Eg : Essential HTN, DM, Morbid Obesity, Anemia

Class 3

Severe systemic disturbance that may or may not be
related to the reason for surgery, (does limit activity)
Eg ; Uncontrolled HTN, DM with vascular complications,
COPD with func. Limitation, angine pectoris, Hx of MI

Class 4

Severe systemic disturbance that is life-threatening with
or without surgery
Eg : CHF, advanced pulmonary, renal/hepatic dysfunction

Class 5

Moribund patient who has little chance of survival but is
submitted to surgery as a last resort (resuscitative effort)
Eg : Uncontrolled hemorrhage from ruptured abdominal
aneurysm, cerebal trauma, pulmonary embolism.

Emergency (E)

Any patient in whom an emergency operation is required
Risk Stratification
5 FACTORS FOR RISK STRATIFICATION
– Recency Of Coronary Revascularization
– Recency Of Last Favourable Cardiac Evaluation
– Presence Of Comorbidities-clinical Predictors
– Functional Status
– Risk Of Proposed Surgery
1-CORONARY REVASCULARISATION

•

Complete coronary surgical revascularization -5 yrs

•

PCI-- > 6months-5 yrs

•

No recurrent Symptoms or signs of ischemia

•

Clinical status is stable

No further cardiac testing is necessary
2-Coronary evaluation
• Past 2 years
• Invasive/non invasive tech
– Favorable
– No definite change or new symptom

No further cardiac testing is necessary
3-Clinical predictors
• Major
– Unstable coronary syndromes
• recent MI with evidence for ischemia ( >7 days & < 30days)
• unstable or severe angina

– Decompensated CHF
– Significant arrhythmia
• high grade AV block
• symptomatic ventricular arrhythmia
• supraventricular arrhythmia with uncontrolled rate

– Severe valvular disease
• Intermediate
– Mild angina pectoris (Canadian class I or II)
– Prior MI by history or pathological Q waves
– Compensated or prior CHF
– Diabetes mellitus
– Renal impairment (creatinine > 2mg per dL)
– Anemia
– Pulmonary Disease (obstructive/restrictive)
• Minor
– Advanced age
– abnormal ECG (LVH, LBBB, ST-T change)
– Rhythm other than sinus
– Low functional capacity
– History of stroke
– Uncontrolled systemic hypertension
Functional Capacity
• Functional capacity can be expressed as
metabolic equivalents (METs); the resting
or basal oxygen consumption (Vo2) of a
70-kg, 40-year-old man in a resting state
is 3.5 mL per kg per min, or 1 MET.
Duke’s Activity Status Index
• 1 MET
– Can you take care of
self?
– Eat, dress, use toilet?
– Walk indoors in house?
– Walk a block or two on
level at 2-3 mph?
– Do light housework like
dusting or dishes?

• 4 METs
1 MET = 3.5 ml/kg/mt VO2

• 4 METs
Climb a flight of stairs,
walk up hill?
Walk on level at 4 mph?
Run a short distance?
Heavy housework
Golf, bowling, dancing,
doubles tennis
Swimming, singles tennis
football, basketball, skiing
• >10 METs
>10 METs-Excellent
7-10
good
4-7
moderate
≤4
poor
Classification of surgeries according to Risk.

• High

(reported cardiac risk > 5%)

• emergent major operations, esp. in elderly
• aortic and other major vascular procedures
• peripheral vascular procedures
• anticipated prolonged procedure with large fluid
shift/blood loss
• Intermediate

(reported cardiac risk < 5%)

– carotid endarterectomy
– head and neck
– intraperitoneal & intrathoracic
– orthopedic
– prostate
• Low

(reported cardiac risk < 1%)

– endoscopic procedures
– superficial procedure
– cataract
– breast
9 step algorithm
9 step algorithm
9 step algorithm

9 step algorithm
Cardiac Conditions that Need Evaluation and Treatment Before
Surgery
Condition
Unstable coronary
syndromes

Examples
Unstable or severe angina (CCS class III, IV) , Recent
MI

Decompensated HF
Significant Arrhythmias

High Grade AV Block, Mobitz II AV Block, 3rd Degree
AV block, Symptomatic Ventricular Arrhythmias,
Supraventricular Arrhytmias with HR > 100 bpm at
rest, Symptomatic Bradycardia, Newly Recognized
VT

Severe Valvular Disease

Severe aortic stenosis, Symptomatic Mitral Stenosis
(dyspnea on exertion, exertional presyncope or HF)
•

Class IIA

•

It is probably recommended that patients with functional capacity greater than or
equal to 4 METs without symptoms‡ proceed to planned surgery.

•

It is probably recommended that patients with poor (less than 4 METs) or unknown
functional capacity and 3 or more clinical risk factors who are scheduled for vascular
surgery consider testing if it will change management.

•

It is probably recommended that patients with poor (less than 4 METs) or unknown
functional capacity and 3 or more clinical risk factors who are scheduled for
intermediate risk surgery proceed with planned surgery with heart rate control.

•

It is probably recommended that patients with poor (less than 4 METs) or unknown
functional capacity and 1 or 2 clinical risk factors who are scheduled for vascular or
intermediate risk surgery proceed with planned surgery with heart rate control.
•

Class IIB

•

Noninvasive testing might be considered if it will change management for patients
with poor (less than 4 METs) or unknown functional capacity and 3 or more clinical
risk factors∥ who are scheduled for intermediate risk surgery.

•

Noninvasive testing might be considered if it will change management for patients
with poor (less than 4 METs) or unknown functional capacity and 1 or 2 clinical risk
factors∥ who are scheduled for vascular or intermediate risk surgery.
PREOP TESTING
• ECG
• DETECT LVH,BBB & CONDUCTION DEFECT
• PREVIOUS MI
• BASELINE FOR INTRA AND POST OP COMPARISON
• INCREASED PERIOP RISK
• ST DEPRESSION MORE THAN .5 MM
• LVH WITH STAIN PATTERN
• LBBB
• EXERCISE STRESS TEST
•

STRONGEST DETERMINANT OF RISK AND NEED FOR
INVASIVE MONITORING

•

LEAD SELECTION

•

ECG CRITERIA
–
–
–
–

1 M M OF J POINT DEPRESSION
2MM OF ST DEPRESSION AT 80 MS FROM J POINT
ST ELEVATION
NON ECG RESP
• LOW ACHIEVED HR
• SYSTOLIC HYPOTENSION
• INABILITY TO EXERCISE FOR MORE THAN 3 MIN
PHARMACOLOGICAL STRESS TEST

• Two Categories
– Dobutamine Stress Echo-incr. Mvo2
– New/Incr In Rwma
– More Than 5/16 Lt Ventricular Segm Involvement

– Dipyridamole Thallium-mimics Coronary Art
Dialatation Resp Associated With Exercise
– Infarcted Area-fixed Defect
– Ischemic Area-reversible Defect
ECHOCARDIOGRAPHY

– LVEF
– RWMA
– Valvular Abn
– Cong Cardiac Defects
CORONARY ANGIOGRAPHY

• Non Invasive Testing-high Risk Of Adverse
Outcome
• Angina Unresponsive To adequate Medical
Therapy
• Unstable Angina-intermediate And High Risk Sx
• High Clinical Predictor In High Risk Sx
PERIOP THERAPY
•

BETA BLOCKERS
– CVS EFFECTS
•
•
•
•

↓ HR-(diastolic Time)
↓ Contractility
Plaque Stabilization- ↓ Shear Forces
Antiarrythmic Effect

– ELIGIBILITY CRITERIA
• CLINICAL -ANY 2
–
–
–
–
–

AGE>65
HTN
CHR SMOKER
SER CHOLESTROL>240 mg/dl
DM

• CARDIAC RISK INDEX CRITERIA
–
–
–
–
–

HIGH RISK SX PROCEDURE
IHD
CVA
DM
CRF
OTHER THERAPIES
•

Alpha-2 Adrenergic Agonist

•

Regional Anesthesia
– Epidural
ACC AHA Guidelines on Perioperative Cardiac Assesement

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ACC AHA Guidelines on Perioperative Cardiac Assesement

  • 1. Overview • Drafted out by American College of Cardiology (ACC) and American Heart Association (AHA) initially in 1980 then revised again in 2002, 2007 and 2011. • Comprising almost 20 topics relating to cardiac issues for patients undergoing non cardiac surgery. • Eg : preoperative noninvasive evaluation of LV function; preoperative resting 12-lead ECG; noninvasive stress testing before non-cardiac surgery; reoperative coronary revascularization; betablocker therapy; statin therapy; preoperative ICU monitoring; use of volatile anesthetic agents; prophylactic Nitroglycerin, maintenance of normothermia; glucose control; use of pulmonary artery catheters; intraoperative and postoperative ST-segment monitoring; surveillance for perioperative myocardial infarction; and the tissue of when patients with cardiac stents can safely undergo elective surgery
  • 2. Purpose • Quick reference for decision making • lower the risk of surgery • evaluation of the patient’s current medical status • make recommendations concerning the evaluation, management, and risk of cardiac problems over the entire preoperative period • provide a clinical risk profile can be of use in making treatment decisions that may influence short- and long-term cardiac outcomes
  • 3. GOALS – IDENTIFICATION OF PATIENTS WITH UNSTABLE CARDIOVASCULAR CONDITION – IDENTIFICATION OF PATIENTS WITH KNOWN AND SYMPTOMATIC Coronary Heart Disease (CHD) – IDENTIFICATION OF PATIENTS AT RISK OF CHD » » » » » PVD HTN DM SMOKING HYPERCHOLESTROLEMIA
  • 5. CLASS 1 CLASS II A CLASS II B CLASS III SHOULD REASONABLE MAYBE CONSIDERED SHOULD NOT Benefit >>> Risk LEVEL A Multiple (3-5) population risk LEVEL B Limited (2-3) population risk LEVEL C Very limited (1-2) population risk BENEFIT >> RISK BENEFIT > RISK RISK > BENEFIT
  • 6. PREOPERATIVE CARDIAC EVALUATION • Evaluation History taking • to identify serious cardiac conditions such as unstable coronary syndromes, prior angina, recent or past MI, decompensated HF, significant arrhythmias, and severe valvular disease • history of a pacemaker or implantable cardioverter defibrillator • Accurate recording of current medications used, including herbal and other nutritional supplements, and dosages .
  • 7. • Determine ASA status , surgery classification and functional capacity. Status State Class 1 No organic, physiologic, biochemical, or psychiatric disturbance. Class 2 Mild to moderate systemic disturbance that may or may not be related to the reason for surgery Eg : Essential HTN, DM, Morbid Obesity, Anemia Class 3 Severe systemic disturbance that may or may not be related to the reason for surgery, (does limit activity) Eg ; Uncontrolled HTN, DM with vascular complications, COPD with func. Limitation, angine pectoris, Hx of MI Class 4 Severe systemic disturbance that is life-threatening with or without surgery Eg : CHF, advanced pulmonary, renal/hepatic dysfunction Class 5 Moribund patient who has little chance of survival but is submitted to surgery as a last resort (resuscitative effort) Eg : Uncontrolled hemorrhage from ruptured abdominal aneurysm, cerebal trauma, pulmonary embolism. Emergency (E) Any patient in whom an emergency operation is required
  • 8. Risk Stratification 5 FACTORS FOR RISK STRATIFICATION – Recency Of Coronary Revascularization – Recency Of Last Favourable Cardiac Evaluation – Presence Of Comorbidities-clinical Predictors – Functional Status – Risk Of Proposed Surgery
  • 9. 1-CORONARY REVASCULARISATION • Complete coronary surgical revascularization -5 yrs • PCI-- > 6months-5 yrs • No recurrent Symptoms or signs of ischemia • Clinical status is stable No further cardiac testing is necessary
  • 10. 2-Coronary evaluation • Past 2 years • Invasive/non invasive tech – Favorable – No definite change or new symptom No further cardiac testing is necessary
  • 11. 3-Clinical predictors • Major – Unstable coronary syndromes • recent MI with evidence for ischemia ( >7 days & < 30days) • unstable or severe angina – Decompensated CHF – Significant arrhythmia • high grade AV block • symptomatic ventricular arrhythmia • supraventricular arrhythmia with uncontrolled rate – Severe valvular disease
  • 12. • Intermediate – Mild angina pectoris (Canadian class I or II) – Prior MI by history or pathological Q waves – Compensated or prior CHF – Diabetes mellitus – Renal impairment (creatinine > 2mg per dL) – Anemia – Pulmonary Disease (obstructive/restrictive)
  • 13. • Minor – Advanced age – abnormal ECG (LVH, LBBB, ST-T change) – Rhythm other than sinus – Low functional capacity – History of stroke – Uncontrolled systemic hypertension
  • 14. Functional Capacity • Functional capacity can be expressed as metabolic equivalents (METs); the resting or basal oxygen consumption (Vo2) of a 70-kg, 40-year-old man in a resting state is 3.5 mL per kg per min, or 1 MET.
  • 15. Duke’s Activity Status Index • 1 MET – Can you take care of self? – Eat, dress, use toilet? – Walk indoors in house? – Walk a block or two on level at 2-3 mph? – Do light housework like dusting or dishes? • 4 METs 1 MET = 3.5 ml/kg/mt VO2 • 4 METs Climb a flight of stairs, walk up hill? Walk on level at 4 mph? Run a short distance? Heavy housework Golf, bowling, dancing, doubles tennis Swimming, singles tennis football, basketball, skiing • >10 METs >10 METs-Excellent 7-10 good 4-7 moderate ≤4 poor
  • 16. Classification of surgeries according to Risk. • High (reported cardiac risk > 5%) • emergent major operations, esp. in elderly • aortic and other major vascular procedures • peripheral vascular procedures • anticipated prolonged procedure with large fluid shift/blood loss
  • 17. • Intermediate (reported cardiac risk < 5%) – carotid endarterectomy – head and neck – intraperitoneal & intrathoracic – orthopedic – prostate
  • 18. • Low (reported cardiac risk < 1%) – endoscopic procedures – superficial procedure – cataract – breast
  • 21. 9 step algorithm 9 step algorithm
  • 22. Cardiac Conditions that Need Evaluation and Treatment Before Surgery Condition Unstable coronary syndromes Examples Unstable or severe angina (CCS class III, IV) , Recent MI Decompensated HF Significant Arrhythmias High Grade AV Block, Mobitz II AV Block, 3rd Degree AV block, Symptomatic Ventricular Arrhythmias, Supraventricular Arrhytmias with HR > 100 bpm at rest, Symptomatic Bradycardia, Newly Recognized VT Severe Valvular Disease Severe aortic stenosis, Symptomatic Mitral Stenosis (dyspnea on exertion, exertional presyncope or HF)
  • 23.
  • 24. • Class IIA • It is probably recommended that patients with functional capacity greater than or equal to 4 METs without symptoms‡ proceed to planned surgery. • It is probably recommended that patients with poor (less than 4 METs) or unknown functional capacity and 3 or more clinical risk factors who are scheduled for vascular surgery consider testing if it will change management. • It is probably recommended that patients with poor (less than 4 METs) or unknown functional capacity and 3 or more clinical risk factors who are scheduled for intermediate risk surgery proceed with planned surgery with heart rate control. • It is probably recommended that patients with poor (less than 4 METs) or unknown functional capacity and 1 or 2 clinical risk factors who are scheduled for vascular or intermediate risk surgery proceed with planned surgery with heart rate control.
  • 25. • Class IIB • Noninvasive testing might be considered if it will change management for patients with poor (less than 4 METs) or unknown functional capacity and 3 or more clinical risk factors∥ who are scheduled for intermediate risk surgery. • Noninvasive testing might be considered if it will change management for patients with poor (less than 4 METs) or unknown functional capacity and 1 or 2 clinical risk factors∥ who are scheduled for vascular or intermediate risk surgery.
  • 26. PREOP TESTING • ECG • DETECT LVH,BBB & CONDUCTION DEFECT • PREVIOUS MI • BASELINE FOR INTRA AND POST OP COMPARISON • INCREASED PERIOP RISK • ST DEPRESSION MORE THAN .5 MM • LVH WITH STAIN PATTERN • LBBB
  • 27. • EXERCISE STRESS TEST • STRONGEST DETERMINANT OF RISK AND NEED FOR INVASIVE MONITORING • LEAD SELECTION • ECG CRITERIA – – – – 1 M M OF J POINT DEPRESSION 2MM OF ST DEPRESSION AT 80 MS FROM J POINT ST ELEVATION NON ECG RESP • LOW ACHIEVED HR • SYSTOLIC HYPOTENSION • INABILITY TO EXERCISE FOR MORE THAN 3 MIN
  • 28. PHARMACOLOGICAL STRESS TEST • Two Categories – Dobutamine Stress Echo-incr. Mvo2 – New/Incr In Rwma – More Than 5/16 Lt Ventricular Segm Involvement – Dipyridamole Thallium-mimics Coronary Art Dialatation Resp Associated With Exercise – Infarcted Area-fixed Defect – Ischemic Area-reversible Defect
  • 29. ECHOCARDIOGRAPHY – LVEF – RWMA – Valvular Abn – Cong Cardiac Defects
  • 30. CORONARY ANGIOGRAPHY • Non Invasive Testing-high Risk Of Adverse Outcome • Angina Unresponsive To adequate Medical Therapy • Unstable Angina-intermediate And High Risk Sx • High Clinical Predictor In High Risk Sx
  • 31. PERIOP THERAPY • BETA BLOCKERS – CVS EFFECTS • • • • ↓ HR-(diastolic Time) ↓ Contractility Plaque Stabilization- ↓ Shear Forces Antiarrythmic Effect – ELIGIBILITY CRITERIA • CLINICAL -ANY 2 – – – – – AGE>65 HTN CHR SMOKER SER CHOLESTROL>240 mg/dl DM • CARDIAC RISK INDEX CRITERIA – – – – – HIGH RISK SX PROCEDURE IHD CVA DM CRF
  • 32. OTHER THERAPIES • Alpha-2 Adrenergic Agonist • Regional Anesthesia – Epidural