2. I. Body Tissues
The human body starts out as a single cell when
the sperm fertilizes the egg.
These cells divide into millions of cells that are
specialized for particular functions.
Some become muscle cells, others transparent
lens of the eye, still others into skin cells, etc.
This is called division of labor – where certain
groups of specialized cells perform functions
that benefit the entire organism.
3. I. Body Tissues
The disadvantage of cell specialization is
that if certain groups of cells are disabled or
damaged it could damage the entire
organism.
Ex – The contractions of the heard depend
on a small group of specialized cells. If
these are damaged, the heart will either stop
or function poorly.
4. I. Body Tissues
Groups of cells that are similar in structure
and function are called tissues.
There are 4 primary tissues types LEARN
THEM!
– Epithelium - covering
– Connective - support
– Nervous - control
– Muscle - movement
5. II. Epithelial Tissue
Makes up the lining, covering, and
glandular tissue of the body.
Functions of epithelium include:
– Protection
– Absorption
– Filtration
– Secretion
6. II. Epithelial Tissue
General Characteristics
– Fit closely together to form continuous sheets.
– The membranes always have one free
(unattached) surface called the apical surface
the other side it attached to a basement
membrane.
– They have no blood supply of their own. They
depend on diffusion from capillaries.
– Can regenerate easily.
7. III. Classification of
Epithelium
Epithelium can be classified in general
terms as either:
– Simple (one layer of cells) or
– Stratified (more than one cell layer.
8. I. Classification of
Epithelium
Types of Simple Epithelia – Since they are
thin, they usually are not involved with
protection, but rather absorption, secretion,
and filtration.
9. III. Classification of Epithelium
Simple Squamous
Epithelium
– Single layer of thin
squamous cells resting on a
basement membrane.
– Fit together like floor tiles.
– Located in air sacs of
lungs, capillary walls, and
covers organs in ventral
cavity
10. III. Classification of Epithelium
Simple Cuboidal
Epithelium
– One layer of cuboidal
cells resting on a
basement membrane
– Common in glands and
ducts
– Walls of kidney
tubules and covers the
surface of the ovaries
11. III. Classification of Epithelium
Simple Columnar
Epithelium
– Single layer of tall
cells that fit closely
together.
– Goblet cells, which
produce lubricating
muscus.
– Entire length of
digestive tract from
stomach to anus.
– Mucous membranes
12. III. Classification of Epithelium
Pseudostratified Columnar Epithelium
– All cells rest on basement membrane
– Some are shorter than others giving the false
impression that it is stratified (made up of more
than one layer)
– Lines respiratory tract
13. III. Classification of Epithelium
Stratified Epithelia consists of 2 or more
cell layers. These are primarily made for
protection.
14. III. Classification of Epithelium
Stratified squamous – most common in body
– Several layers of cells.
– Free edge is squamous. Cells close to basement membrane is
either cuboidal or columnar.
– Esophagus, mouth, outer part of skin. High use areas.
15. III. Classification of Epithelium
Stratified cuboidal and
Stratified Columnar
– 2 cell layers with surface
being cuboidal in shape
– Surface cells of Stratified
columnar are columnar
cells, but basal cells vary in
size and shape.
– Both are rare in body and
only found in the ducts of
large glands.
16. III. Classification of Epithelium
Transitional
Epithelium
– Highly modified
stratified sqamous
epithelium
– Forms lining of
urinary bladder,
ureters, and part
of the urethra.
– Aids in stretching
17. III. Classification of Epithelium
Glandular Epithelium
– Gland consists of one or more cells that make and
secrete a particular product.
– Product is called a secretion.
– Two types of glands
Endocrine glands – (ductless glands) – Diffuse into the
blood to be used in the body – include thyroid,
adrenals, and pituitary
Exocrine glands – (retain their ducts) – Empty through
ducts to the epithelial surface – include sweat and oil
glands, liver, and pancrease.
18. I. Connective Tissue
Connects body parts.
Found everywhere in the body.
Most abundant and widely distributed of all
body tissue types.
19. IV. Connective Tissue
Common characteristics
– Most are well vascularized (good blood supply)
except for tendons and ligaments with poor
blood supply and cartilages which are avascular.
These heal poorer than the well vascularized
tissue.
– Extracellular Matrix – made up of different
types of cells plus varying amounts of a
nonliving substance outside the cells called
extracellular maxtrix.
20. IV. Connective Tissue
Extracellular matrix is what makes
connective tissue different from all other
tissue types.
Produced by connective tissue cells and
secreted to their exterior.
Matrix may be liquid, semisolid, gel-like or
very hard.
Can bear weight, can stretch, can take abuse.
21. IV. Connective Tissue
Different degrees of strength
– Fat tissue is mostly cells with a soft matrix
– Bone and cartilage have few cells and large amounts
of hard matrix which makes them extremely strong.
– Fibers that make up the matrix are
Collagen fibers (white)
Elastic fibers (yellow)
Reticular fibers (fine collagen)
Protecting, support, binding together
22. V. Types of Connective Tissue
Most important thing to remember about the
different tissue types is
– Fiber type
– Number of fibers
From most rigid to the softest are =
– Bone, cartilage, dense connective tissue, loose
connective tissue, and blood.
23. V. Types of Connective Tissue
Bone
– AKA osseous tissue composed of bone cells
sitting in cavities called lacunae and surrounded
by layers of a very hard matrix that contains
calcium slats and large numbers of collagen
fibers.
– Exceptional protection and support
24. V. Types of Connective Tissue
Cartilage
– Less hard and more flexible than bone.
– Few places in the body.
– The most common type is hyaline cartilage.
Abundant collagen fibers hidden by a rubbery matrix with
a glassy blue-white appearance.
Attaches ribs to breastbone, covers ends of bone, fetus
skeleton
– Elastic cartilage – external ear
– Fibrocartilage – vertebral disks
25. V. Types of Connective Tissue
Dense Connective Tissue
– AKA dense fibrous tissue
– Collagen fibers as main matrix
– Crowded between collagen fibers are rows of
fibroblasts (fiber-forming cells) that make fibers.
– Make up tendons (attach muscles to bones) and
ligaments (connect bones to bones)
– Ligaments are more stretchy and contain more
elastic fibers that tendons.
– Makes up lower layers of skin
26. V. Types of Connective Tissue
Loose Connective Tissue
– Softer, have more cells and fewer fibers than
the other types
27. V. Types of Connective Tissue
Types of Loose Connective Tissue
– Areolar Tissue – soft tissue that cushions and
protects body organs.
Universal packing and glue to hold the internal organs
together.
When viewed under the microscope it appears to be
mostly open space.
– Adipose Tissue – commonly called fat tissue
Oil occupies most of the cell compressing nucleus. Cell
looks empty.
Subcutaneous tissue beneath skin, insulates body, protects
organs, stored for energy in hips, stomach, and breasts.
28. V. Types of Connective Tissue
Reticular Connective Tissue
– Delicate network of interwoven reticular fibers
associate with reticular cells which resemble
fibrobasts.
– Located in lymphoid organs such as lymph
nodes, spleen, and bone marrow.
29. V. Types of Connective Tissue
Blood
– AKA vascular tissue
– Blood cells surrounded by a non-living matrix
called blood plasma.
– The fibers of blood are soluble protein
molecules that become visible only during
blood clotting
– Carries nutrients, waste, respiratory gases and
other substances throughout the body.
30. VI. Types of Muscle Tissue
There are three types of muscle tissue.
– Skeletal muscle is packaged by connective tissue
into sheets which are attached to the bones.
These are voluntary muscles (you control
them).
Usually called meat or flesh
When they contract they pull on bones or skin
causing body movements and facial
expressions.
They are striated.
31. VI. Types of Muscle Tissue
– Cardiac Muscle
Only found in the heart.
Acts as a pump and propels blood through
the blood vessels.
It has striations, but cells are uninucleate,
branching cells that fit tightly together.
(intercalated disks)
Involuntary muscle – we cannot consciously
control the activity.
32. VI. Types of Muscle Tissue
– Smooth Muscle
AKA visceral muscle
No striations are visible.
Single nucleus and spindle-shaped (pointed at each
end)
Found in the walls of hollow organs (stomach,
bladder, uterus, blood vessels)
Muscle contraction forces movement through the
organ.
Much slower than other types of muscles.
Involuntary
Peristalsis – wavelike motion that keeps food
moving through the small intestine.
33. VII. Nervous Tissue
Composed of cells called
neurons
– Highly specialized to
receive and transmit nerve
impulses and supporting
cells.
– Neurons are important in
controlling body
processes
– Found in brain, spinal
cord, and nerves.
34. VIII. Tissue Repair
Two ways of tissue repair:
– Regeneration – Tissue is replaced
with the same kind of cells
– Fibrosis – Repair by dense (fibrous)
connective tissue (scar tissue)
35. VIII. Tissue Repair
Which type of repair occurs depends
on
– The type of tissue damaged
– The severity of the injury
Clean cuts (incisions) heal much more
successfully than ragged tears
(lacerations)
36. VIII. Tissue Repair
Steps to Tissue Repair
– Clotting proteins create a clot which stops the
loss of blood, holds the edges of the wound
together and prevents bacteria and other
harmful substances from spreading to
surrounding tissues
– Clot dries and forms a scab.
37. VIII. Tissue Repair (con’t)
– Granulation tissue forms next
Pink tissue composed largely of capillaries that
grow into the damaged area from undamaged blood
vessels nearby.
Fragile and bleed freely when scab is scraped away.
Contains phagocytes and get rid of the blood clot
and connective tissue cells that make collagen fibers
that permanently bridge the gap.
– While all this is going on, epithelium grows
back together covering the scar tissue.
38. VIII. Tissue Repair
The scar is either invisible or visible
depending on the severity of the wound
Epithelial tissues such as skin and mucous
membranes regenerate beautifully as do
most of the fibrous connective tissue and
bone.
Skeletal muscles regenerate poorly, if at all,
and cardiac muscle and nervous tissue are
replaced only by scar tissue.
39. VIII. Tissue Repair
Scar tissue is strong, but lacks flexibility.
It cannot perform the normal functions of
the tissue it replaces.
If scar tissue forms in the wall of the
bladder, heart, or other muscular organ, it
may SEVERELY hamper the functioning
of that organ.
40. IX. Developmental Aspects of
Tissues
Know some stages of aging (pg 86)
Neoplasm – Then cells multiply wildly an
an abnormal mass of proliferating cells
results. Can be either benign or malignant.
Hyperplasia – Normal increase in certain
body tissues or organs
Atrophy – decrease in the size of an organ
due to non-use.