4. The midbrain is a portion of the
central nervous system
associated with vision, hearing,
motor control, sleep/wake,
arousal (alertness), and
temperature regulation
5. DIVISION OF THE MIDBRAIN
MIDBRAIN
CEREBRAL
PEDUNCLE
CRUS
CERBRI
TEGMENTUM
TECTUM
SUPERIOR
COLLICULUS
INFERIOR
COLLICULUS
6.
7. AT THE LEVEL OF THE INFERIOR
COLLICULUS
CAVITY
NUCLEI
MOTOR TRACTS
SENSORY TRACTS
10. The substantia nigra
is divisible into a dorsal part, the pars
compacta; and a ventral part, the pars
reticularis. The pars compacta contains
dopaminergic and cholinergic neurons. Most
of the neurons in
Superiorly, the pars reticularis becomes
continuous with the globus
pallidus.
The substantia nigra is closely connected,
functionally, with the corpus striatum (and in
causation
of Parkinsonism,
11.
12. TRACTS
SENSORY
• TRIGEMINAL
• SPINAL
• MEDIAL
• LATERAL
• DECUSSATION OF SUPERIOR CERBELLAR
PEDUNCLE
MOTOR
• CORTICOSPINAL
• CORTICONUCLEAR
• TEMPOROPONTINE
• FRONTOPONTINE
• MED. LONG. FASCICULUS
13. AT THE LEVEL OF THE SUPERIOR
COLLICULUS
CAVITY
NUCLEI
MOTOR TRACTS
SENSORY TRACTS
21. Medial midbrain syndrome (paramedian
branches of upper basilar and proximal posterior cerebral
arteries)
ON SIDE OF LESION
Eye "down and out"
secondary to unopposed
action of fourth and sixth
cranial nerves, with
dilated and unresponsive
pupil: Third nerve fibers
ON OPPOSITE SIDE
Paralysis of face, arm,
and leg: Corticobulbar
and corticospinal tract
descending in crus
cerebri
22.
23. Lateral midbrain syndrome (syndrome of small
penetrating arteries arising from posterior cerebral artery)
On side of lesion
Eye "down and out"
secondary to unopposed
action of fourth and sixth
cranial nerves, with
dilated and unresponsive
pupil: Third nerve fibers
and/or third nerve nucleus
On side opposite lesion
Hemiataxia,
hyperkinesias, tremor:
Red nucleus,
dentatorubrothalamic
pathway
24. Weber’s syndrome
injury to the cerebral peduncle
causes ipsilateral
oculomotor palsy with
contralateral hemiparesis
33. is a form of brainstem stroke
syndrome characterized by the presence
of an ipsilateral oculomotor nerve palsy,
contralateral hemiparesis,
contralateral ataxia, and
contralateral hemiplegia of the lower face,
tongue, and shoulder. Claude's syndrome
affects occulomotor nerve,red nucleus and
brachium conjunctivum
34.
35. Parinaud's Syndrome
also known as dorsal midbrain
syndrome, vertical gaze palsy, and Sunset
Sign, is an inability to move the eyes up. It is
caused by compression of the vertical gaze
center at the rostral interstitial nucleus of
medial longitudinal fasciculus
36.
37. Conjugate down gaze in the primary
position: "setting-sun sign".
Neurosurgeons see this sign most
commonly in patients with
failed hydrocephalus shunts.
38. it has been associated with three major
groups:
Young patients with brain tumors in
the pineal
gland or midbrain: pinealoma (intracranial
germinomas) are the most common lesion
producing this syndrome.
Women in their 20s-30s with multiple
sclerosis
Older patients following stroke of the
upper brainstem
39.
40. any other compression, ischemia or
damage to this region can produce these
phenomena: obstructive hydrocephalus,
midbrain hemorrhage, cerebral
arteriovenous malformation, trauma and
brainstem toxoplasmosis infection.
Neoplasms and giant aneurysms of
the posterior fossa have also been
associated with the midbrain syndrome.