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SARANG SURESH HOTCHANDANI
Non neoplastic soft tissue
swellings of mouth arising from
oral mucosa.
What we learn here?
SARANG SURESH HOTCHANDANI 2
Fibrous Nodule
 Most common soft tissue swellings of mouth.
 Appear as hyperplastic swellings at those sites
where minor chronic injury OR low grade infection occurs.
 NODULE; Well circumscribed solid, elevated lesion more
than 5mm in diameter.
SARANG SURESH HOTCHANDANI 3
Epulis/Epulides; it is fibrous nodule on gingiva.
Denture induced granuloma; these are fibrous
nodules formed in denture wearers.
Fibrous Polyp; it is fibrous nodule growing on
buccal mucosa.
Fibrous Nodule
SARANG SURESH HOTCHANDANI 4
 Usually caused by irritation of gingival margin by;
 Sharp edges of carious cavity
 Calculus
 Mostly occur on anterior teeth in interdental area.
 Lesion is usually firm, pink in color & non –
ulcerated.
Epulis
SARANG SURESH HOTCHANDANI 5
3 types of Epulis are present.
Fibrous Epulis; most common
Vascular Epulis
Giant Cell Granuloma; approx. in 10% of
cases.
Epulis
SARANG SURESH HOTCHANDANI 6
Common Features to all Epulis;
Common in females.
Mostly on anterior teeth.
More common in MAXILLA
Epulis
SARANG SURESH HOTCHANDANI 7
Recurrence Rate of Epulis
HIGHEST; Giant Cell
Granuloma
lowest; Fibrous Epulis
SARANG SURESH HOTCHANDANI 8
Present as pedunculated or sessile mass
Firm in consistency and has similar color to
normal gingiva.
May or may not be ulcerated.
If ulceration is present, lesion is covered by
yellowish fibrinoid exudate.
Mostly b/w 11 – 40 years of age.
Fibrous Epulis
SARANG SURESH HOTCHANDANI 9
Cellular fibrous granulation tissue.
Mature collagen fibre bundles
Plasma cell infiltrate
Deposits of calcification or trabeculae of
metaplastic bone are found within
granulation tissue.
Fibrous Epulis
(Histological Features)
SARANG SURESH HOTCHANDANI 10
Excise along with small base of
normal tissue to prevent recurrence.
Curette the underlying bone of nodule
after excision.
Treatment of Fibrous Nodule
SARANG SURESH HOTCHANDANI 11
 Appear as soft, deep red or purple swelling.
 Usually ulcerated & haemorrhaging with spontaneous or
minor trauma.
 Classified into two types Clinically;
 Pyogenic granuloma
 Pregnancy Epulis
Vascular Epulis
SARANG SURESH HOTCHANDANI 12
It is pyogenic granuloma in pregnant patients
Usually at the end of 1st trimester.
After delivery may regress spontaneously or
converted to fibrous Epulis.
Excision of this lesion should be avoided
before conversion to fibrous because of risk of
excessive haemorrhage.
Pregnancy Epulis
SARANG SURESH HOTCHANDANI 13
Dilated blood vessels or
vascular proliferation in
oedematous connective tissue
stroma
Vascular Epulis (Histology)
SARANG SURESH HOTCHANDANI 14
 Polyp is a swelling with narrow base.
 Usually appear on buccal mucosa along occlusal line
 Usually caused by chronic cheek bite, ulceration uncommon.
 Lesion appear as firm, painless, polyp covered by mucosa of
normal appearance.
 One established does not grow further.
Fibrous Polyp
SARANG SURESH HOTCHANDANI 15
 Sometimes surface is white due to frictional
keratosis.
 Histological features;
 Core of dense, avascular and acellular fibrous tissue with
interlacing bundles of collagen fibres covered by hyperplastic
stratified squamous epithelium which is sometimes hyperketosed.
Fibrous Polyp
SARANG SURESH HOTCHANDANI 16
 It is produced by irritation of alveolar or palatal mucosa by
roughened area on denture.
 Usually forms at margins of denture.
 Most frequently at lower denture.
 These all types of fibrous nodules are pale and firm, but they
can be abraded and ulcerated and inflammation can occur later.
Denture Granuloma
SARANG SURESH HOTCHANDANI 17
This is also fibrous hyperplasia but does
not produce swelling.
Usually are flat and develop b/w denture
& mucosa (not on denture margins unlike
denture granuloma)
Leaf Fibroma
SARANG SURESH HOTCHANDANI 18
 It is variant of fibrous Epulis and can be found only on
histological examination.
 It is characterized by containing large, mono nucleate, stellate &
darkly stained cells b/w short coarse fibrous tissue bundles.
 Clinically they are pedunculated & usually arise from gingiva or
tip of tongue.
Giant Cell Fibroma
SARANG SURESH HOTCHANDANI 19
 They are benign epithelial tumour growing exophytically
(outward projecting).
 Clinical Features;
 Spiky, exophytic or round cauliflower like.
 Aetiology;
 Human Papilloma Virus
Papilloma
SARANG SURESH HOTCHANDANI 20
 Oral papilloma are non premalignant.
 Squamous Cell Papilloma
 Mainly affects Adults.
 Appear as cauliflower like or finger like
 Mostly white due to keratinization.
 Histology
 The papilla consists of vascular connective tissue core surrounded by
squamous epithelium.
Papilloma
SARANG SURESH HOTCHANDANI 21
 Aka Giant Cell Epulis
 Males ~ 20 years & Females ~ 50 years
 Mostly occur on anterior teeth.
 Mostly occur in MANDIBLE
 Female to Male Ratio ~ 2:1
Peripheral Giant Cell Granuloma
SARANG SURESH HOTCHANDANI 22
 Clinical Features
 Present as pedunculated, sessile swelling of varying size.
 Dark red, maroon or purplish in colour & commonly
ulcerated.
 Usually occur on marginal gingiva.
 Sometimes associated with recently lost deciduous teeth.
 Usually occur on interdental areas and may have
hourglass shape due to joining of buccal & lingual
swelling.
Peripheral Giant Cell Granuloma
SARANG SURESH HOTCHANDANI 23
Radiographic Features
Shows superficial erosion of crest of
interdental bone/alveolar margin.
Radiograph is required to reach diagnosis
because sometimes central giant cell
granuloma may perforate the cortex of
alveolar bone & appear as peripheral giant cell
granuloma.
Peripheral Giant Cell Granuloma
SARANG SURESH HOTCHANDANI 24
Histological Features
Focal collections of multinucleated osteoclast like
giant cells separated by fibrous septa in vascular or
cellular stoma.
The lesion is covered by stratified squamous
epithelium.
A narrow fibrous tissue separate the core lesion
from stratified squamous epithelium.
Peripheral Giant Cell Granuloma
SARANG SURESH HOTCHANDANI 25
 Present as numerous, small, tightly packed papillary
projection over denture bearing area of palate.
 Gives hard palate Pebbled Appearance.
 Mucosa is often Red & oedematous, sometimes
associated with candidiasis.
Papillary Hyperplasia of Palate
SARANG SURESH HOTCHANDANI 26
AETIOLOGY
Ill fitting denture
Poor oral hygiene
Sleeping with dentures
Papillary Hyperplasia of Palate
SARANG SURESH HOTCHANDANI 27
Histology
Lesion shows papillary projections having
core of hyperplastic, chronically inflamed
granulation tissue covered by hyperplastic
stratified squamous tissue.
Papillary Hyperplasia of Palate
SARANG SURESH HOTCHANDANI 28
Management
Clean denture
Avoid wearing denture overnight
Antifungal drugs for candidiasis
Papillary Hyperplasia of Palate
SARANG SURESH HOTCHANDANI 29
Final Year BDS Student
Bibi Aseefa Dental College
Shaheed Mohtarma Benazir Bhutto
Medical University
Larkana, Sindh
PAKISTAN
SARANG SURESH
HOTCHANDANI
SARANG SURESH HOTCHANDANI 30

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Common Benign Mucosal Swellings of Oral Cavity

  • 2. Non neoplastic soft tissue swellings of mouth arising from oral mucosa. What we learn here? SARANG SURESH HOTCHANDANI 2
  • 3. Fibrous Nodule  Most common soft tissue swellings of mouth.  Appear as hyperplastic swellings at those sites where minor chronic injury OR low grade infection occurs.  NODULE; Well circumscribed solid, elevated lesion more than 5mm in diameter. SARANG SURESH HOTCHANDANI 3
  • 4. Epulis/Epulides; it is fibrous nodule on gingiva. Denture induced granuloma; these are fibrous nodules formed in denture wearers. Fibrous Polyp; it is fibrous nodule growing on buccal mucosa. Fibrous Nodule SARANG SURESH HOTCHANDANI 4
  • 5.  Usually caused by irritation of gingival margin by;  Sharp edges of carious cavity  Calculus  Mostly occur on anterior teeth in interdental area.  Lesion is usually firm, pink in color & non – ulcerated. Epulis SARANG SURESH HOTCHANDANI 5
  • 6. 3 types of Epulis are present. Fibrous Epulis; most common Vascular Epulis Giant Cell Granuloma; approx. in 10% of cases. Epulis SARANG SURESH HOTCHANDANI 6
  • 7. Common Features to all Epulis; Common in females. Mostly on anterior teeth. More common in MAXILLA Epulis SARANG SURESH HOTCHANDANI 7
  • 8. Recurrence Rate of Epulis HIGHEST; Giant Cell Granuloma lowest; Fibrous Epulis SARANG SURESH HOTCHANDANI 8
  • 9. Present as pedunculated or sessile mass Firm in consistency and has similar color to normal gingiva. May or may not be ulcerated. If ulceration is present, lesion is covered by yellowish fibrinoid exudate. Mostly b/w 11 – 40 years of age. Fibrous Epulis SARANG SURESH HOTCHANDANI 9
  • 10. Cellular fibrous granulation tissue. Mature collagen fibre bundles Plasma cell infiltrate Deposits of calcification or trabeculae of metaplastic bone are found within granulation tissue. Fibrous Epulis (Histological Features) SARANG SURESH HOTCHANDANI 10
  • 11. Excise along with small base of normal tissue to prevent recurrence. Curette the underlying bone of nodule after excision. Treatment of Fibrous Nodule SARANG SURESH HOTCHANDANI 11
  • 12.  Appear as soft, deep red or purple swelling.  Usually ulcerated & haemorrhaging with spontaneous or minor trauma.  Classified into two types Clinically;  Pyogenic granuloma  Pregnancy Epulis Vascular Epulis SARANG SURESH HOTCHANDANI 12
  • 13. It is pyogenic granuloma in pregnant patients Usually at the end of 1st trimester. After delivery may regress spontaneously or converted to fibrous Epulis. Excision of this lesion should be avoided before conversion to fibrous because of risk of excessive haemorrhage. Pregnancy Epulis SARANG SURESH HOTCHANDANI 13
  • 14. Dilated blood vessels or vascular proliferation in oedematous connective tissue stroma Vascular Epulis (Histology) SARANG SURESH HOTCHANDANI 14
  • 15.  Polyp is a swelling with narrow base.  Usually appear on buccal mucosa along occlusal line  Usually caused by chronic cheek bite, ulceration uncommon.  Lesion appear as firm, painless, polyp covered by mucosa of normal appearance.  One established does not grow further. Fibrous Polyp SARANG SURESH HOTCHANDANI 15
  • 16.  Sometimes surface is white due to frictional keratosis.  Histological features;  Core of dense, avascular and acellular fibrous tissue with interlacing bundles of collagen fibres covered by hyperplastic stratified squamous epithelium which is sometimes hyperketosed. Fibrous Polyp SARANG SURESH HOTCHANDANI 16
  • 17.  It is produced by irritation of alveolar or palatal mucosa by roughened area on denture.  Usually forms at margins of denture.  Most frequently at lower denture.  These all types of fibrous nodules are pale and firm, but they can be abraded and ulcerated and inflammation can occur later. Denture Granuloma SARANG SURESH HOTCHANDANI 17
  • 18. This is also fibrous hyperplasia but does not produce swelling. Usually are flat and develop b/w denture & mucosa (not on denture margins unlike denture granuloma) Leaf Fibroma SARANG SURESH HOTCHANDANI 18
  • 19.  It is variant of fibrous Epulis and can be found only on histological examination.  It is characterized by containing large, mono nucleate, stellate & darkly stained cells b/w short coarse fibrous tissue bundles.  Clinically they are pedunculated & usually arise from gingiva or tip of tongue. Giant Cell Fibroma SARANG SURESH HOTCHANDANI 19
  • 20.  They are benign epithelial tumour growing exophytically (outward projecting).  Clinical Features;  Spiky, exophytic or round cauliflower like.  Aetiology;  Human Papilloma Virus Papilloma SARANG SURESH HOTCHANDANI 20
  • 21.  Oral papilloma are non premalignant.  Squamous Cell Papilloma  Mainly affects Adults.  Appear as cauliflower like or finger like  Mostly white due to keratinization.  Histology  The papilla consists of vascular connective tissue core surrounded by squamous epithelium. Papilloma SARANG SURESH HOTCHANDANI 21
  • 22.  Aka Giant Cell Epulis  Males ~ 20 years & Females ~ 50 years  Mostly occur on anterior teeth.  Mostly occur in MANDIBLE  Female to Male Ratio ~ 2:1 Peripheral Giant Cell Granuloma SARANG SURESH HOTCHANDANI 22
  • 23.  Clinical Features  Present as pedunculated, sessile swelling of varying size.  Dark red, maroon or purplish in colour & commonly ulcerated.  Usually occur on marginal gingiva.  Sometimes associated with recently lost deciduous teeth.  Usually occur on interdental areas and may have hourglass shape due to joining of buccal & lingual swelling. Peripheral Giant Cell Granuloma SARANG SURESH HOTCHANDANI 23
  • 24. Radiographic Features Shows superficial erosion of crest of interdental bone/alveolar margin. Radiograph is required to reach diagnosis because sometimes central giant cell granuloma may perforate the cortex of alveolar bone & appear as peripheral giant cell granuloma. Peripheral Giant Cell Granuloma SARANG SURESH HOTCHANDANI 24
  • 25. Histological Features Focal collections of multinucleated osteoclast like giant cells separated by fibrous septa in vascular or cellular stoma. The lesion is covered by stratified squamous epithelium. A narrow fibrous tissue separate the core lesion from stratified squamous epithelium. Peripheral Giant Cell Granuloma SARANG SURESH HOTCHANDANI 25
  • 26.  Present as numerous, small, tightly packed papillary projection over denture bearing area of palate.  Gives hard palate Pebbled Appearance.  Mucosa is often Red & oedematous, sometimes associated with candidiasis. Papillary Hyperplasia of Palate SARANG SURESH HOTCHANDANI 26
  • 27. AETIOLOGY Ill fitting denture Poor oral hygiene Sleeping with dentures Papillary Hyperplasia of Palate SARANG SURESH HOTCHANDANI 27
  • 28. Histology Lesion shows papillary projections having core of hyperplastic, chronically inflamed granulation tissue covered by hyperplastic stratified squamous tissue. Papillary Hyperplasia of Palate SARANG SURESH HOTCHANDANI 28
  • 29. Management Clean denture Avoid wearing denture overnight Antifungal drugs for candidiasis Papillary Hyperplasia of Palate SARANG SURESH HOTCHANDANI 29
  • 30. Final Year BDS Student Bibi Aseefa Dental College Shaheed Mohtarma Benazir Bhutto Medical University Larkana, Sindh PAKISTAN SARANG SURESH HOTCHANDANI SARANG SURESH HOTCHANDANI 30