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SHUBHAM KUMAR VISHWAKARMA
5th sem B.Pharm
Haematuria-- presence of blood in urine
A hematinic is a nutrient required for the formation
of blood cells in the process of hematopoiesis. The
main hematinics are iron, B12, and folate. Deficiency
in hematinics can lead to anaemia. In cases of
hematinic deficiency, hematinics can be administered
as medicines, in order to increase
the hemoglobin content of the blood.
Erythropoietin (EPO) is a hormone that
stimulates erythropoiesis
How the interaction occurs
 Your medicine contains aluminum, calcium, iron, lanthanum,
magnesium, and/or zinc, which are cations that may bind to
your antibiotic in your digestive tract. This prevents your body
from absorbing the antibiotic.
What might happen:
The blood levels of your antibiotic may be decreased, which will
decrease the effectiveness in treating your infection.
 Allergi
 Liver disfunction
• Amoxicilline & clavulenic acid 3 g ( beeta
lactmase inhibitor) antibiotic
• Use in bacterial infection
• Eg UIT, wound healing
• Mean corpuscular
volume (MCV)
laboratory test
• completeblood count
(CBC)
• mean corpuscular
hemoglobin
concentration
(MCHC) test
• Stomach & intestinal problem eg ulcer, colitis
• Tetracycline antibiotics
• Thyroid medication (levo thyroxine)
• Antibiotics – ciprofloxacine , quinolones , levofloxacine
• Iron Metabolism Disorder causing Increased Iron Storage
• Ulcerated Colon
Iron salts are often available in combinations
with "absorption stimulating" additives (e.g.
ascorbic acid) and as gastric juice-resistant
and slow-release preparations. These special
preparations probably do not offer any
relevant advantage compared to mono-
preparations.
• Penicillamine interacts with IRON
Penicillamine is used for Wilson's disease and
rheumatoid arthritis. Iron might decrease how
much penicillamine your body absorbs and
decrease the effectiveness of penicillamine. To
avoid this interaction take iron two hours before
or two hours after taking penicillamine.
Side Effects
Constipation, diarrhea, stomach cramps,
or upset stomach may occur. These effects are
usually temporary and may disappear as your
body adjusts to this medication
Iron may cause your stools to turn black, an
effect that is not harmful.
Hematinics classification
Oral preparations
Ferrous gluconate
Ferrous sulphate
Ferrous fumarate
Colloidal ferric hydroxide
Carbonyl iron sulphate
Ferrous succinate
Ferrous glycine
Ferric glycerophosphate
Ferrous ammonium citrate
Ferrous aminoate
Ferric hydroxide polymaltose
Parenteral
Iron dextran
lron sorbitol citrate complex
Iron sucrose
Iron dextrin (polymaltose)
Vitamin B12
Cyanocobalamin
Methylcobalamin
Hydroxycobalamin
• Hematopoietic Growth Factors
•
Erythropoietin
• Darbepoietin
Sources
Hematinics
Hematinics
Hematinics

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Hematinics

  • 2.
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  • 26. Haematuria-- presence of blood in urine
  • 27.
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  • 33.
  • 34. A hematinic is a nutrient required for the formation of blood cells in the process of hematopoiesis. The main hematinics are iron, B12, and folate. Deficiency in hematinics can lead to anaemia. In cases of hematinic deficiency, hematinics can be administered as medicines, in order to increase the hemoglobin content of the blood. Erythropoietin (EPO) is a hormone that stimulates erythropoiesis
  • 35. How the interaction occurs  Your medicine contains aluminum, calcium, iron, lanthanum, magnesium, and/or zinc, which are cations that may bind to your antibiotic in your digestive tract. This prevents your body from absorbing the antibiotic. What might happen: The blood levels of your antibiotic may be decreased, which will decrease the effectiveness in treating your infection.  Allergi  Liver disfunction
  • 36. • Amoxicilline & clavulenic acid 3 g ( beeta lactmase inhibitor) antibiotic • Use in bacterial infection • Eg UIT, wound healing
  • 37.
  • 38. • Mean corpuscular volume (MCV) laboratory test • completeblood count (CBC) • mean corpuscular hemoglobin concentration (MCHC) test
  • 39. • Stomach & intestinal problem eg ulcer, colitis • Tetracycline antibiotics • Thyroid medication (levo thyroxine) • Antibiotics – ciprofloxacine , quinolones , levofloxacine • Iron Metabolism Disorder causing Increased Iron Storage • Ulcerated Colon
  • 40. Iron salts are often available in combinations with "absorption stimulating" additives (e.g. ascorbic acid) and as gastric juice-resistant and slow-release preparations. These special preparations probably do not offer any relevant advantage compared to mono- preparations.
  • 41. • Penicillamine interacts with IRON Penicillamine is used for Wilson's disease and rheumatoid arthritis. Iron might decrease how much penicillamine your body absorbs and decrease the effectiveness of penicillamine. To avoid this interaction take iron two hours before or two hours after taking penicillamine.
  • 42. Side Effects Constipation, diarrhea, stomach cramps, or upset stomach may occur. These effects are usually temporary and may disappear as your body adjusts to this medication Iron may cause your stools to turn black, an effect that is not harmful.
  • 43.
  • 44.
  • 45.
  • 46.
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  • 61.
  • 62.
  • 63.
  • 64.
  • 65.
  • 66.
  • 67.
  • 68.
  • 69.
  • 70. Hematinics classification Oral preparations Ferrous gluconate Ferrous sulphate Ferrous fumarate Colloidal ferric hydroxide Carbonyl iron sulphate Ferrous succinate Ferrous glycine Ferric glycerophosphate Ferrous ammonium citrate Ferrous aminoate Ferric hydroxide polymaltose
  • 71. Parenteral Iron dextran lron sorbitol citrate complex Iron sucrose Iron dextrin (polymaltose) Vitamin B12 Cyanocobalamin Methylcobalamin Hydroxycobalamin
  • 72. • Hematopoietic Growth Factors • Erythropoietin • Darbepoietin
  • 73.
  • 74.
  • 75.
  • 76.