An overview of NeXO Web, and web application for integrated ontology visualization.

1. Keiichiro Ono (kono@ucsd.edu)
University of California, San Diego Department of Medicine
What is NeXO Web?
NeXO WebAn Integrated Ontology Visualization Application for Modern Web Platforms
Technologies
Gene Ontology Visualizations
Search & Term Enrichment
Analysis Window
Ontology Tree (DAG) View
Raw Interaction View
Term Details
A gene ontology inferred from molecular networks. Janusz Dutkowski, Michael Kramer, Michal A Surma,
Rama Balakrishnan, J Michael Cherry, Nevan J Krogan & Trey Ideker. Nature Biotechnology 31, 38–45
(2013).
NeXO (Network eXtracted Ontology) is a data-driven gene ontology inferred directly from
‘omics data. The NeXO Web application is designed to visualize the NeXO data sets and
existing ontologies, such as GO, utilizing modern web technologies.
- Provides a new way to visualize ontology data sets with modern web technologies
- Integrate multi-omics data into a HTML5-based Single Page Application (SPA)
- Open for future expansion
Theoritical Background
NeXO Web: the NeXO ontology database and visualization platform. Dut-
kowski J, Ono K, Kramer M, Yu M, Pratt D, Demchak B, Ideker T. Nucleic
Acids Res. 2014 Jan;42 (Database issue)
Thechnical Background
nexontology.org
sigma.js
Client-Side Server-Side
Cytoscape.js