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Eye color
Different colors
Brown
Blue
Grey
Green
Blue-green?
Blue
Green
Blue
Brown?
Grey-blue?
Browny-green (Hazel)
Grey with a little brown
Blue – or grey?
Looks grey – is it real?
Obviously NOT real
Who cares, anyway?
How about these guys?
Neanderthal man
What color were their eyes?
Who knows?
Who cares?
How can we find out?
DNA samples?
Remember Jurassic Park?
Fossilized mosquito!!
Take out some blood
Whose blood?
The blood of a neanderthal man!!
Get a DNA sample
Bring back lost people
No … I don’t want to come back!!
I don’t like modern humans
OK … different animals
Bring these back
Great idea
We can do it!
We have the cloning technology
Really?
We really have the cloning
technology?
No, not really!
Don’t be stupid.
It’s just a movie!
But scientists CAN analyze DNA
That’s kind of clever
For example?
Get DNA from bones
Figure out eye color
Figure out eye color?
Yes
Not cloning dinosaurs?
No
Who is going to study that?!
Molecular biologists
Exciting!
Eye color and DNA
We can predict eye color!
Kind of …
To a certain extent
Predict eye color?!
Parents’ eyes, children’s eyes
Two brown eyed parents
• 75% chance brown
• 19% chance blue
• 7% chance green
One brown one blue
• 50% chance brown
• 50% chance blue
• 0% chance green
That’s SO exciting!
Who needs this?
We can predict EYE COLOR!!!!
Actually, some people care
Forensic scientists
Computer forensics
Forensic molecular biology
Forensic science
Elementary, my dear Watson
Actually, it’s NOT elementary
It’s very complicated
Analysing DNA to solve crimes
DNA swab test
Maybe you commit a crime
We get a sample of your DNA
You are the criminal
I am Poirot
I don’t need DNA
I am a fictional detective
How do they do it?
Study molecular biology
Chromosome
Long strand of DNA
DNA consists of many genes
Genes carry code
Eye color, blood type, etc
Genes are segments of DNA
Certain genes determine eye color
• Eight genes for eye color
• Two are the strongest predictors
• But they ALL have an influence
Forensic science
Must be very accurate
Must be VERY careful
Modern forensic scientists …
… use computers
Computer models of genetic variation
NOT like this!
DNA samples
Eye color data
From 6,000 people
Information into the computer
Great!
I’m a forensic molecular biologist
Call me FMB
Give me your DNA sample!
Give it to me!!
OK, here it is!
Here’s my DNA sample
OK, I’ve analyzed your DNA sample
I used my fantastic computer model!
Now I will predict your eye color!!
Using my fantastic computer model!
Why don’t you just look at my eyes?
Shut up!
I will use my great computer model
OK, I’ve finished.
Your eyes are blue
No, they are brown
Never mind. Only 90% accuracy for
blue and brown
Why didn’t you just look at my eyes?
Shut up! This is forensic science
90% accuracy for blue and brown
70% for other colors
The future is bright
We can predict everything!
Your hair is red!
Your designer baby’s hair will be blue
Wait … designer babies?
Is that a good idea?
Should we be able to decide
EVERYTHING?
Even change things about our babies?
Change a baby’s DNA?
Should scientists really be involved in
this?
Can we trust scientists?
Is it natural?
What if you gave a DNA sample …
… then three weeks later …
… the police come to your door …
… and say, we compared your DNA …
… with DNA at a murder scene.
You are a murderer!
You are a murderer!
You are a murderer!
My computer model says so!
Now let me make a T Rex

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Eye color