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Research unit in molecular biology housen -UNamur- Lab'inSight Bioresources
1.
30/07/13 1 RESEARCH UNIT IN MOLECULAR BIOLOGY FUNDP – Faculty of Science Dr. Isabelle HOUSEN – Researcher URBM FIELDS OF EXPERTISE IN BIORESOURCES ENGINEERING & CHEMISTRY Bacterial, yeast, fungal genome exploitaLon • Iden-fica-on and isola-on of genes •
Produc-on of protein of interest Gene engineering and expression of the modified protein : • Understanding of the structure‐func-on rela-onship • Modifica-on of its physico‐chemical proper-es ModificaLon of a microorganism : • Metal trapping for environmental purposes • Altera-on of op-mal pH or temperature for industrial processes 2 Gembloux – March 1st 2012
2.
30/07/13 2 APPLIED RESEARCH PROJECTS Examples of company‐oriented projects Modifica-ons of an hydrolase enzyme to obtain sugars with a higher degree of polymerisa-on, more resistant to hydrolyse Valorisa-on of sub‐products of agriculture into prebio-cs
Engineering of bacterial strains to capture metal ions from the environment 3 Gembloux – March 1st 2012 SERVICES PROVIDED TO COMPANIES Screening and characterizaLon of secreted hydrolases from various organisms (yeast, fungus, bacterium, …) for their iden-fica-on and full characteriza-on of their coding sequence for their engineering and produc-on for tailored industrial purposes 4 Gembloux – March 1st 2012
3.
30/07/13 3 OPPORTUNITIES FOR COMPANIES Screening various organisms for genes of interest CharacterizaLon and engineering of enzymes of interest (secretome) Scale‐up producLon of proteins
Development and applicaLon of methods to follow sugar hydrolysis (chemical dosage, thin layer chromatography, …) 5 Gembloux – March 1st 2012 Agro‐food Industry LAB CONTACT INFORMATION Dr. Isabelle HOUSEN Researcher isabelle.housen@fundp.ac.be ‐ Phone : +32 81 72 44 08 Research Unit in Molecular Biology
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