BLAST(Basic Local Alignment Tool)

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The Basic Local Alignment Search Tool (BLAST) for comparing gene and protein sequences against others in public databases.

Formation Technologie

Any important work that does not begin with Bismillah is imperfect.

(Basic local alignment search Tool) Fast similarity searching of the database

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Insert your sequence in FASTA format Submit your search

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An integrated publicly accessible bioinformatics resource to support genomic/proteomic research and scientific discovery. Established in 1984, by the National Biomedical Research Foundation (NBRF) Georgetown University Medial Center, Washington D.C., USA. It is the source of annotated protein databases and analysis tools for the researchers. Serve as primary resource for the exploration of protein information. Accessible by text search for entry and list retrieval, and also BLAST search and peptide match.

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Bioinformatics involves the analysis of biological information using computers and statistical techniques, In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. The sequence alignment is made between a known sequence and unknown sequence or between two unknown sequences. The known sequence is called reference sequence. The unknown sequence is called query sequence . BLAST stands for Basic Local Alignment Search Tool. It addresses a fundamental problem in bioinformatics research. BLAST tool is used to compare a query sequence with a library or database of sequences. In Bioinformatics, is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences. BLAST was developed by stochastic model of Samuel Karlin and Stephen Altschul in 1990. They proposed “a method for estimating similarities between the known DNA sequence of one organism with that of another”. A BLAST search enables a researcher to compare a subject protein or nucleotide sequence (called a query sequence) with a library or database of sequences and identify database sequences that resemble the query sequence above a certain threshold.

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Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life. Two segments of DNA can have shared ancestry because of three phenomena: either a speciation event (orthologs), or a duplication event (paralogs), or else a horizontal (or lateral) gene transfer event (xenologs).[1] Homology among DNA, RNA, or proteins is typically inferred from their nucleotide or amino acid sequence similarity. Significant similarity is strong evidence that two sequences are related by evolutionary changes from a common ancestral sequence. Alignments of multiple sequences are used to indicate which regions of each sequence are homologous.

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BLAST(Basic Local Alignment Tool)

1. Any important work that does not begin with Bismillah is imperfect.

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33. Insert your sequence in FASTA format Submit your search

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