Chronic syndrome of chronic prostatitis / pelvic pain (CP / CPPS) is a very difficult to treat satisfactorily very complex disease, although some patients respond to treatment;
3-As a rule: alpha blockers, antibiotics, anti-inflammatory, is not always effective;
Evaluation of Meares-Stamey test is often negative and antibiotics should be considered with caution;
Long treatment by anti-inflammayorees must be considered with caution because of side effects;
A number of studies have shown the effectiveness of pollen extract should be taken into account and encourage large scale trials to test their effectiveness.
Nevertheless, in some patients, this treatment could be offered.
Pollen extract must to be considered in the treatment of the chronic prostatitis or pelvic pain syndrome
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Pollen and vitamin in chronic prostatitis chronic pelvic pain syndrome
1. Made by @hupertan
New article: Pollen and Vitamin in chronic
prostatitis/chronic pelvic pain syndrome.
Commented and cured Vincent
@Hupertan
Tags: chronic pelvic pain syndrome, chronic prostatitis, #chronicprostatitis,
#pollen extract; #prostatitis syndrome; #prostatitissyndrome, #qualityoflife
2. Made by @hupertan
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Pollen extract in association with vitamins provides early pain relief in patients affected by chronic
prostatitis/chronic pelvic pain syndrome.
Cai T1, Wagenlehner FM2, Luciani LG1, Tiscione D1, Malossini G1, Verze P3, Mirone V3, Bartoletti R4.
Exp Ther Med. 2014 Oct;8(4):1032-1038. Epub 2014 Jul 24.
Abstract
The therapeutic efficacy for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is currently
unsatisfactory. The aim of the present study was to assess the safety and efficacy of pollen extract in
association with vitamins (DEPROX 500®) in males with CP/CPPS. All patients with a diagnosis of
CP/CPPS attending the same urologic centre between March and October 2012 were enrolled in this
randomised controlled phase III study. Participants were randomised to receive oral capsules of DEPROX
500® (two capsules every 24 h) or ibuprofen (600 mg, one tablet three times a day) for four weeks. The
National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), International Prostate
Symptom Score and Quality of Well-Being (QoL) questionnaires were used. In the intention-to-treat
analysis, 87 males (25 class IIIa and 62 class IIIb) with a mean age of 33.6±5.9 years were randomly
allocated to the DEPROX 500® (n=41) or ibuprofen (n=46) treatment groups. At the follow-up
examination (following one month of treatment), in the DEPROX 500® group, 31/41 patients (75.6%)
reported an improvement in quality of life, defined as a reduction of the NIH-CPSI total score by ≥25%,
compared with 19/46 (41.3%) in the control group (P=0.002). The greater improvement in the DEPROX
500® group compared with the ibuprofen group was statistically significant (treatment difference in the
NIH-CPSI pain domain, -2.14±0.51, P<0.001; QoL scores, P=0.002). All patients were negative at the
Meares-Stamey test evaluation. Adverse events were less frequent in the DEPROX 500® group than in
the ibuprofen group. The DEPROX 500® treatment significantly improved total symptoms, pain and
quality of life compared with ibuprofen in patients with CP/CPPS, without severe side-effects.
4. Made by @hupertan
RESULTS
DEPROX 500® group
QoL improvement -
76%
24%
Ibuprofen group (Control)
QoL improvement -
41%
59%
At the follow-up examination (following one month of treatment), in the DEPROX 500® group,
31/41 patients (75.6%) reported an improvement in quality of life, defined as a reduction of the
NIH-CPSI total score by ≥25%, compared with 19/46 (41.3%) in the control group (P=0.002).
5. Made by @hupertan
Comments by @hupertan
• Chronic syndrome of chronic prostatitis / pelvic pain (CP / CPPS) is a very
difficult to treat satisfactorily very complex disease, although some
patients respond to treatment;
• 3-As a rule: alpha blockers, antibiotics, anti-inflammatory, is not always
effective;
• Evaluation of Meares-Stamey test is often negative and antibiotics should
be considered with caution;
• Long treatment by anti-inflammayorees must be considered with caution
because of side effects;
• A number of studies have shown the effectiveness of pollen extract should
be taken into account and encourage large scale trials to test their
effectiveness.
• Nevertheless, in some patients, this treatment could be offered.
6. Made by @hupertan
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