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Made by @hupertan 
New article: Pollen and Vitamin in chronic 
prostatitis/chronic pelvic pain syndrome. 
Commented and cured Vincent 
@Hupertan 
Tags: chronic pelvic pain syndrome, chronic prostatitis, #chronicprostatitis, 
#pollen extract; #prostatitis syndrome; #prostatitissyndrome, #qualityoflife
Made by @hupertan 
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id11903422/item123273777
Made by @hupertan 
Pollen extract in association with vitamins provides early pain relief in patients affected by chronic 
prostatitis/chronic pelvic pain syndrome. 
Cai T1, Wagenlehner FM2, Luciani LG1, Tiscione D1, Malossini G1, Verze P3, Mirone V3, Bartoletti R4. 
Exp Ther Med. 2014 Oct;8(4):1032-1038. Epub 2014 Jul 24. 
Abstract 
The therapeutic efficacy for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is currently 
unsatisfactory. The aim of the present study was to assess the safety and efficacy of pollen extract in 
association with vitamins (DEPROX 500®) in males with CP/CPPS. All patients with a diagnosis of 
CP/CPPS attending the same urologic centre between March and October 2012 were enrolled in this 
randomised controlled phase III study. Participants were randomised to receive oral capsules of DEPROX 
500® (two capsules every 24 h) or ibuprofen (600 mg, one tablet three times a day) for four weeks. The 
National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), International Prostate 
Symptom Score and Quality of Well-Being (QoL) questionnaires were used. In the intention-to-treat 
analysis, 87 males (25 class IIIa and 62 class IIIb) with a mean age of 33.6±5.9 years were randomly 
allocated to the DEPROX 500® (n=41) or ibuprofen (n=46) treatment groups. At the follow-up 
examination (following one month of treatment), in the DEPROX 500® group, 31/41 patients (75.6%) 
reported an improvement in quality of life, defined as a reduction of the NIH-CPSI total score by ≥25%, 
compared with 19/46 (41.3%) in the control group (P=0.002). The greater improvement in the DEPROX 
500® group compared with the ibuprofen group was statistically significant (treatment difference in the 
NIH-CPSI pain domain, -2.14±0.51, P<0.001; QoL scores, P=0.002). All patients were negative at the 
Meares-Stamey test evaluation. Adverse events were less frequent in the DEPROX 500® group than in 
the ibuprofen group. The DEPROX 500® treatment significantly improved total symptoms, pain and 
quality of life compared with ibuprofen in patients with CP/CPPS, without severe side-effects.
Made by @hupertan 
RESULTS 
DEPROX 500® group 
QoL improvement - 
76% 
24% 
Ibuprofen group (Control) 
QoL improvement - 
41% 
59% 
At the follow-up examination (following one month of treatment), in the DEPROX 500® group, 
31/41 patients (75.6%) reported an improvement in quality of life, defined as a reduction of the 
NIH-CPSI total score by ≥25%, compared with 19/46 (41.3%) in the control group (P=0.002).
Made by @hupertan 
Comments by @hupertan 
• Chronic syndrome of chronic prostatitis / pelvic pain (CP / CPPS) is a very 
difficult to treat satisfactorily very complex disease, although some 
patients respond to treatment; 
• 3-As a rule: alpha blockers, antibiotics, anti-inflammatory, is not always 
effective; 
• Evaluation of Meares-Stamey test is often negative and antibiotics should 
be considered with caution; 
• Long treatment by anti-inflammayorees must be considered with caution 
because of side effects; 
• A number of studies have shown the effectiveness of pollen extract should 
be taken into account and encourage large scale trials to test their 
effectiveness. 
• Nevertheless, in some patients, this treatment could be offered.
Made by @hupertan 
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Pollen and vitamin in chronic prostatitis chronic pelvic pain syndrome

  • 1. Made by @hupertan New article: Pollen and Vitamin in chronic prostatitis/chronic pelvic pain syndrome. Commented and cured Vincent @Hupertan Tags: chronic pelvic pain syndrome, chronic prostatitis, #chronicprostatitis, #pollen extract; #prostatitis syndrome; #prostatitissyndrome, #qualityoflife
  • 2. Made by @hupertan • Vincent Hupertan (the "Author”) is an independent blogger, with many social media accounts, including Twitter (hupertan), Linkedin (Hupertan), Google+ (+ DrHupertan), Facebook (DrVHupertan), Wordpress (Hupertan) , SlideShare, etc • Is otherwise hospital doctor, registered in the Council of the College of Physician Paris with RPPS number: 1000 39 70 315 and Order No: 75 1 68044 8. His acitivity as author, blogger, tweeter is fully exercised privately. • The document whose content Hupertan Vincent is the author and the information contained therein are provided by the author for educational purposes and are not intended to provide medical advice. • You acknowledge your understanding that the site should not be used as a substitute for a notice of by a health professional accredited to your country. • By accessing the following slides, you understand and acknowledge that there is no physician-patient relationship between you and the author. More information's here http://www.pearltrees.com/hupertan/11-web-responsabilite-medicale/ id11903422/item123273777
  • 3. Made by @hupertan Pollen extract in association with vitamins provides early pain relief in patients affected by chronic prostatitis/chronic pelvic pain syndrome. Cai T1, Wagenlehner FM2, Luciani LG1, Tiscione D1, Malossini G1, Verze P3, Mirone V3, Bartoletti R4. Exp Ther Med. 2014 Oct;8(4):1032-1038. Epub 2014 Jul 24. Abstract The therapeutic efficacy for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is currently unsatisfactory. The aim of the present study was to assess the safety and efficacy of pollen extract in association with vitamins (DEPROX 500®) in males with CP/CPPS. All patients with a diagnosis of CP/CPPS attending the same urologic centre between March and October 2012 were enrolled in this randomised controlled phase III study. Participants were randomised to receive oral capsules of DEPROX 500® (two capsules every 24 h) or ibuprofen (600 mg, one tablet three times a day) for four weeks. The National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), International Prostate Symptom Score and Quality of Well-Being (QoL) questionnaires were used. In the intention-to-treat analysis, 87 males (25 class IIIa and 62 class IIIb) with a mean age of 33.6±5.9 years were randomly allocated to the DEPROX 500® (n=41) or ibuprofen (n=46) treatment groups. At the follow-up examination (following one month of treatment), in the DEPROX 500® group, 31/41 patients (75.6%) reported an improvement in quality of life, defined as a reduction of the NIH-CPSI total score by ≥25%, compared with 19/46 (41.3%) in the control group (P=0.002). The greater improvement in the DEPROX 500® group compared with the ibuprofen group was statistically significant (treatment difference in the NIH-CPSI pain domain, -2.14±0.51, P<0.001; QoL scores, P=0.002). All patients were negative at the Meares-Stamey test evaluation. Adverse events were less frequent in the DEPROX 500® group than in the ibuprofen group. The DEPROX 500® treatment significantly improved total symptoms, pain and quality of life compared with ibuprofen in patients with CP/CPPS, without severe side-effects.
  • 4. Made by @hupertan RESULTS DEPROX 500® group QoL improvement - 76% 24% Ibuprofen group (Control) QoL improvement - 41% 59% At the follow-up examination (following one month of treatment), in the DEPROX 500® group, 31/41 patients (75.6%) reported an improvement in quality of life, defined as a reduction of the NIH-CPSI total score by ≥25%, compared with 19/46 (41.3%) in the control group (P=0.002).
  • 5. Made by @hupertan Comments by @hupertan • Chronic syndrome of chronic prostatitis / pelvic pain (CP / CPPS) is a very difficult to treat satisfactorily very complex disease, although some patients respond to treatment; • 3-As a rule: alpha blockers, antibiotics, anti-inflammatory, is not always effective; • Evaluation of Meares-Stamey test is often negative and antibiotics should be considered with caution; • Long treatment by anti-inflammayorees must be considered with caution because of side effects; • A number of studies have shown the effectiveness of pollen extract should be taken into account and encourage large scale trials to test their effectiveness. • Nevertheless, in some patients, this treatment could be offered.
  • 6. Made by @hupertan If you like this slide, please «Tweet» / «Like it» / «Pin it» / «Share.it» with your friends, students, colleagues....