Quelle est la place de l'Optiflow aux urgences ?
Où en est-on des études cliniques ?
Peut-on traiter les patients des urgences comme ceux de réanimation avec l'oxygénation haut-débit ?
De nouvelles perspectives avec l'Optiflow ?
19. Spoletini G, et al. Chest. 2015;148(1):253-61
Effets bénéfiques…
20. Spoletini G, et al. Chest. 2015;148(1):253-61
Pratique clinique…
21. Sztrymf et al. Int Care Med. 2011
Rittayamai et al. Respir Care. 2014
Lenglet et al. Respir Care. 2012
Rittayamai et al. Respir Care. 2015
Etat de l’art…
27. Lenglet H, et al. Respir Care 2012;57(11):1873-8.
Pneumonia was the most common reason for
oxygen therapy (9/17)
HFNC is possible in the ED, and it alleviated
dyspnea and improved respiratory parameters in
subjects with acute hypoxemic respiratory failure.
Humidified High Flow Nasal Oxygen During
Respiratory Failure in the Emergency Department:
Feasibility and Efficacy
Pionniers…
29. HOT-ER
Jones PG et al. Respir Care 2016
CONCLUSIONS: HFNC was not shown to reduce the need for mechanical ventilation
in the emergency department for subjects with acute respiratory distress compared with
standard O2, although it was safe and may reduce the need for escalation of oxygen
therapy within the first 24 h of admission
C’est de l’Urgence !!
35. IRA
Durey A, et al . Am J Emerg Med. 2017;70(4):465-472
In our study, cardiogenic pulmonary edema was observed more frequently
in the success group and the finding of bilateral pulmonary infiltrates on
chest X-ray was more common in the success group as well.
Whereas, the percentage of pneumonia was higher in the failure group.
39. CONCLUSIONS
A novel strategy for preoxygenation in hypoxaemic patients, adding HFNC for apnoeic
oxygenation to NIV prior to orotracheal intubation, may be more effective in reducing
the severity of oxygen desaturation than the reference method using NIV alone.
Pré-oxygénation Réa
41. On y travaille…
Hayes-Bradley C, et al. An Emerg Med 2016
Efficacy of Nasal Cannula Oxygen as a
Preoxygenation Adjunct in Emergency
Airway Management
Clare Hayes-Bradley, BSc, MBBS*; Anthony Lewis, MBBCh, PhD; Brian Burns, MBBCh, MSc; Matt Miller, MBChB
*Corresponding Author. E-mail: clarehayesbradley@yahoo.com, Twitter: @ClareHBradley.
Study objective: Although preoxygenation for emergency airway management is usually performed with nonrebreather
face masks or bag-valve-mask devices, some clinicians also deliver supplemental high-flow oxygen by nasal cannula.
We aim to measure the efficacy of supplemental nasal cannula oxygen delivery to conventional bag-valve-mask and
nonrebreather face mask preoxygenation both with and without a simulated face mask leak.
Methods: We conducted a randomized crossover trial using healthy volunteers. We randomized subjects to
preoxygenation with bag-valve-mask or nonrebreather face mask. In random sequence, subjects underwent 3-minute
trials of preoxygenation with oxygen through mask alone at 15 L/min, oxygen through mask at 15 L/min with standardized
leak, oxygen through mask at 15 L/minþoxygen through nasal cannula at 10 L/min, and oxygen through mask at 15 L/
minþoxygen through nasal cannula at 10 L/min with standardized leak. The primaryoutcome was single-breath exhalation
end-tidal oxygen (ETO2). We compared ETO2 between preoxygenation modalities, using nonparametric techniques.
Results: We enrolled 60 subjects (30 nonrebreather face mask and 30 bag-valve-mask). In scenarios without a mask
leak, ETO2 was similar between bag-valve-mask and bag-valve-maskþnasal cannula (mean 79% versus 75%; difference
–3%; 95% confidence interval [CI] –8% to 1%). In bag-valve-mask scenarios with a mask leak, ETO2 was higher for bag-
valve-maskþnasal cannula than bag-valve-mask alone (mean 66% versus 41%; difference 25%; 95% CI 21% to 29%).
ETO2 was higher for nonrebreather face maskþnasal cannula than nonrebreather face mask (mean 67% versus 52%;
difference 15%; 95% CI 12% to 18%). In nonrebreather face mask scenarios with a mask leak, ETO2 was higher for
nonrebreather face maskþnasal cannula than nonrebreather face mask (mean 65% versus 48%; difference 17%; 95%
CI 13% to 20%).
Conclusion: Although not aiding bag-valve-mask preoxygenation with a good mask seal, supplemental nasal cannula
oxygen improved preoxygenation efficacy in the presence of a bag-valve-mask mask leak. Supplemental nasal cannula
oxygen improved nonrebreather face mask preoxygenation both with and without a mask leak. Supplemental nasal
AIRWAY/ORIGINAL RESEARCH
What this study adds to our knowledge
In this randomized trial on 60 healthy volunteers,
nasal cannula oxygen at 10 L/min improved end-tidal
oxygen levels with nonrebreather mask,
nonrebreather with a mask leak, and bag-valve-mask
with a mask leak. Addition of nasal cannula did not
improve end-tidal oxygen with well-sealed bag-valve-
mask.
How this is relevant to clinical practice
Although requiring validation in clinical emergency
department patients, supplemental nasal cannula
oxygen may aid emergency airway management
preoxygenation efforts.